Vol 16, No 3 (June 30, 2025) - Journal of Gastrointestinal Oncology

Original Article

Efficacy and safety of concurrent radiotherapy and chemotherapy for locally advanced esophageal squamous cell carcinoma: a randomized controlled trial

Jialiang Zhou, Erwen Bao, Gang Wu, Qiang Fan, Yutian Zhao, Yunxia Zhang, Wei Wu, Zhenwu Wang, Fuzheng Zhang, Kuaile Zhao

PDF Pages: 791-801 Full Text (194) Reporting Checklist Trial Protocol Data Sharing Statement COI Form Open Access

Clinical and endoscopic characteristics of colorectal sessile serrated lesion with dysplasia: a single-center cross-sectional comparative study

Yanping Wu, Yunrong Wang, Bei Zhao, Yifan Li, Weiwei Wang, Wenqi Sun, Longying Xiong, Dan Ge, Jiale Xu, Xiaotan Dou, Xiaoping Zou, Wen Li, Lei Wang, Min Chen

PDF Pages: 802-810 Full Text (123) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Genes associated with calcium signaling have promising diagnostic potential for gastric cancer

Chao Shen, Yichao Yan, Bin Liang, Ji Shi, Yan Wu, Ning Ning, Lin Chen, Ankit Madan, Wei Li

PDF Pages: 811-822 Full Text (91) Reporting Checklist Peer Review File COI Form Open Access

CDK12 inhibition enhances oxaliplatin efficacy in gastric cancer by suppressing the MAPK signaling pathway

Dayin Huang, Zhizhong Xiong, Bin Zhong, Xianwen Li, Saddam Ahmed Mohamed, Jiachen Sun, Haoyang Xu, Jianping Guo, Zijian Deng, Xianzhe Li, Khaldoun Almhanna, Yonghe Chen, Lei Lian

PDF Pages: 823-839 Full Text (115) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

TRIP6/c-Fos regulating GPX4 modulates gastric cancer growth by inhibiting ferroptosis

Yang Huang, Wentao Zhang, Jilong Shen, Yongxiang Li

PDF Pages: 840-852 Full Text (69) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Toosendanin induces ferroptosis in gastrointestinal stromal tumor cells through the regulation of the NCOA4 ferritinophagy pathway: implications for tumor proliferation, migration, and invasion

Qiao Feng, Yuxi Li, Lincan Zhong, Huwei Nie, Wensheng Yang, Guangyu Chen, Lin Zhang

PDF Pages: 853-864 Full Text (68) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Predictive value of preoperative subcutaneous and intramuscular adipose tissue for the occurrence of postoperative liver metastasis in gastric cancer patients undergoing radical gastrectomy

Di Dai, Zhengyuan Bao, Yinsu Zhu, Meiqin Wang

PDF Pages: 865-874 Full Text (54) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Development and validation of a preoperative CT-based body composition nomogram for predicting recurrence-free survival after radical surgery in patients with gastric cancer

Anyi Song, Zhaoheng Huang, Jiahuan Xu, Jinghao Chen, Haipeng Gong, Chunyan Yang, Zhengqi Zhu

PDF Pages: 875-889 Full Text (112) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Impact of cancer-directed surgery for gastric cancer patients with lung metastasis: a prognosis analysis

Zhongyu Tan, Xiyao Du, Mo Zeng, Yingli Huang, Yunlong Cai, Shanshan Huang

PDF Pages: 890-898 Full Text (77) Reporting Checklist Peer Review File COI Form Open Access

D-dimer predicts the response of patients with gastric cancer to first-line immunotherapy combined with chemotherapy

Longyu Xu, Yang Li, Kai Wang, Chaomin Liu, Rong Liu, Wenjing Zhang

PDF Pages: 899-908 Full Text (79) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Treatment discontinuation associated with perioperative toxicity of FLOT versus XELOX chemotherapy in patients with resectable gastric cancer: prospective randomized trial (PECORINO)

Oleksii Dobrzhanskyi, Vjacheslav Kopetskyi, Eric A. Ross, Jonathan Chernoff, Yevhenii Shudrak, Andrii Kolesnyk, Mykyta Pepenin, Andrii Horodetskyi, Nelja Melnitchouk, Yurii Kondratskyi

PDF Pages: 909-921 Full Text (115) Reporting Checklist Trial Protocol Data Sharing Statement Peer Review File COI Form Open Access

Development and validation of a LASSO-based nomogram for predicting anastomotic leakage in elderly patients after laparoscopic gastrectomy

Na Yang, Ying Deng

PDF Pages: 922-936 Full Text (77) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Automated machine learning predicts liver metastases in patients with early-onset gastroenteropancreatic neuroendocrine tumors

Fuli Gao, Jian Chen, Xiaodan Xu

PDF Pages: 937-949 Full Text (72) Reporting Checklist Peer Review File COI Form Open Access

A prognostic nomogram utilized lymph node ratio for signet ring cell gastric cancer patients post-surgery

Chao Peng, Ting Li

PDF Pages: 950-964 Full Text (72) Reporting Checklist Peer Review File COI Form Open Access

The diagnostic efficiency of tissue factor pathway inhibitor 2 methylation in the detection of colorectal cancer: a systematic review and meta-analysis

Xiao-Ling Wang, Shuo Qin, Li Liu, Yu-Qi Jia, Ying Wang, Yu-Jie Zhou, Bruno Ramos-Molina, Manuel Valladares-Ayerbes, Moritz Eidens, Zhi-Zhen Liu

PDF Pages: 965-977 Full Text (66) Reporting Checklist Peer Review File COI Form Open Access

A real-world study of oxaliplatin-induced hypersensitivity in colorectal cancer treatment based on the pharmacovigilance system in China: a cohort study

Jing Xue, Chengcui Huang, Chunmei Dai, Jingwen Xie, Mateusz Jagielski, Emmanuel Gabriel, Xiaoyan Li

PDF Pages: 978-985 Full Text (68) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Comprehensive analysis of m6A-related lncRNAs as prognosis factors in the immune microenvironment of colorectal cancer

Tian-Hao Lan, Wei Li, Fei Xu, Fu-Lei Meng, Xing Zhang, Jian-Wei Ma, Ning Yang, Qi-Wei Zhao, Zeng-Ren Zhao

PDF Pages: 986-1000 Full Text (58) Reporting Checklist Peer Review File COI Form Open Access

The significance of lymph node metastasis in pT1-2 colorectal cancer

Bolun Song, Liming Wang, Yinggang Chen, Yasumitsu Hirano

PDF Pages: 1001-1012 Full Text (51) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Impact of occlusal support on postoperative complications in patients with colorectal cancer resections

Masano Sagawa, Hajime Yokomizo, Sachiyo Okayama, Shunsuke Iwamoto, Ryohei Nishiguchi, Shinichi Asaka, Takebumi Usui, Takeshi Shimakawa, Hisashi Yano, Sayaka Yoshiba, Shunichi Shiozawa

PDF Pages: 1013-1024 Full Text (55) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Molecular characterisation of Mozambican patients diagnosed with colorectal adenocarcinoma

Carlos Selemane, Dylan Ferreira, Isabel Veiga, Patrícia Rocha, Luisa Jamisse, Landim Buane, Assucena Guisseve, Carla Carrilho, Mamudo Ismail, Manuel R. Teixeira, Lúcio Lara Santos

PDF Pages: 1025-1037 Full Text (46) Data Sharing Statement Peer Review File COI Form Open Access

Log odds of positive lymph nodes-based staging system for colorectal cancer patients with inadequate lymph nodes harvested: a potential reference for adjuvant chemotherapy

Hongwei Wang, Linlin Wang, Zhong Li, Jiahang Zhang, Guohui Liu

PDF Pages: 1038-1049 Full Text (94) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Efficacy and safety of transcatheter arterial embolization combined with ablation and regorafenib for unresectable hepatocellular carcinoma patients failing first-line treatment: a real-world study

Wenfeng Gao, Yiqi Xiong, Tingting Mei, Christine Pocha, Xavier Adhoute, Pierleone Lucatelli, Yonghong Zhang

PDF Pages: 1050-1059 Full Text (104) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The long noncoding RNA RMRP-miR-3135a-SV2A axis promotes the development of hepatocellular carcinoma

Ying Wang, Chao Chen, Haozhe Huang, Lichao Xu, Francisco Tustumi, Jun Liu, Wentao Li

PDF Pages: 1060-1077 Full Text (42) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Long-term outcomes of indeterminate focal hepatic observations less than 20 mm followed up with gadoxetic acid-enhanced magnetic resonance imaging (Gd-EOB-DTPA-MRI)

Fei Xing, Yichen Xu, Yue Cao, Lijuan Zhai, Jian Lu, Jifeng Jiang, Qinrong Ma, Wei Xing, Ralf Weiskirchen, Vasileios K. Mavroeidis, Tao Zhang, Songhua Ma

PDF Pages: 1078-1091 Full Text (58) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Identification and validation of a ferroptosis-related long non-coding RNA signature as a prognostic biomarker for hepatocellular carcinoma

Tingting Yu, Xiaoxiang Chen, Shuo Li, Morten Ladekarl, Jun Li

PDF Pages: 1092-1104 Full Text (45) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

PANoptosis-associated genes exhibit significant potential in the diagnosis of hepatocellular carcinoma

Yujin Li, Junfeng Li, Yu Chen

PDF Pages: 1105-1114 Full Text (57) Reporting Checklist Peer Review File COI Form Open Access

The molecular sub-type and the development and validation of a prognosis prediction model based on endocytosis-related genes for hepatocellular carcinoma

Liting Zhang, Dan Zhou, Xiaoqin Gao, Junfeng Li, Xiaodong Xie

PDF Pages: 1115-1126 Full Text (45) Reporting Checklist Peer Review File COI Form Open Access

Characterization of T cell proliferation-associated hepatocellular carcinoma subtypes, predictive signatures, and candidate targets

Qi Yang, Le Liu, Yawen Zhu, Zhengchao Shen, Yifan Xu, Mengjie Zhang, Xi Chen

PDF Pages: 1127-1143 Full Text (65) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Lower diffusion-derived vessel density (DDVD) measure of liver focal nodular hyperplasia than those of hepatocellular carcinoma and liver metastasis allows potential differential diagnosis: quantitative and semi-quantitative analyses of two-center data

Cun-Jing Zheng, Dian-Qi Yao, Cai-Ying Li, Xiao-Hui Duan, Ge Zhang, Zhuo-Heng Yan, Guang-Zi Shi, Xin-Ming Li, Jun Shen, Yì Xiáng J. Wáng

PDF Pages: 1144-1156 Full Text (53) Data Sharing Statement Peer Review File COI Form Open Access

Evaluating the combined diagnostic power of alpha-fetoprotein and protein induced by vitamin K absence or antagonist-II for hepatocellular carcinoma

Shangdi Zhang, Caiyan Gao, Yubin Wang, Linmei Chen, Shan Gao

PDF Pages: 1157-1175 Full Text (54) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Expression of PDZ domain-containing proteins is correlated with prognosis and immune infiltration in hepatocellular carcinoma

Xiaozhen Song, Yujia Lin, Chi Wu, Miaoxin Zhang, Longjun Yang, Ninghui Zhao, Panpan Lu, Qiang Ding, Qinghai Tan, Mei Liu

PDF Pages: 1176-1195 Full Text (52) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Comparison analysis of different doses bevacizumab plus ICIs and interventional therapy in unresectable hepatocellular carcinoma: a real-world study

Miao Li, Tong Li, Yi Chen, Ningling Ge, Biwei Yang, Rongxin Chen, Yinghao Shen, Lan Zhang

PDF Pages: 1196-1207 Full Text (59) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A novel miRNA-based model for predicting the 3-year recurrence risk of hepatocellular carcinoma following liver transplantation

Bin Yu, Youming Ding

PDF Pages: 1208-1219 Full Text (47) Reporting Checklist Peer Review File COI Form Open Access

Impact of postoperative chemotherapy on the prognosis of combined hepatocellular-cholangiocarcinoma: a retrospective study based on the SEER database

Yunxi Lu, Lulu Zheng, Huihong Mei

PDF Pages: 1220-1232 Full Text (70) Reporting Checklist Peer Review File COI Form Open Access

Genetically proxied risk and protective factors for pancreatic cancer: a systematic review and meta-analysis of Mendelian randomization studies

Fada Luo, Weicheng Mou, Yong Zeng, Xingwei Ouyang, Richard J. Bold, Somashekar G. Krishna, Atsushi Yamaguchi, Li Zhang

PDF Pages: 1233-1247 Full Text (107) Reporting Checklist Peer Review File COI Form Open Access

Peripheral blood neutrophil-to-lymphocyte ratio as a prognostic marker and its association with the tumor-immune microenvironment in pancreatic cancer: a retrospective cohort study

Jing Li, Jiayi Wang, Yuxuan Li, Wenna Jiang, Duo Zuo, Xiuse Zhang, Jiawei Xiao, Kentaro Inamura, Elisa Giovannetti, Li Ren

PDF Pages: 1248-1257 Full Text (61) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Imaging prediction of lymph node metastasis and early recurrence in patients with distal cholangiocarcinoma

Yizhe Wang, Jingjing Yao, Liang Wang, Zhuozhao Zheng, Chen Zhang, Jie Li

PDF Pages: 1258-1267 Full Text (60) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Real-world effectiveness of anamorelin in patients with unresectable and relapse pancreatic cancer: a prospective observational study

Atsushi Yamaguchi, Hiroki Kamada, Shigeaki Semba, Naohiro Kato, Yuji Teraoka, Takeshi Mizumoto, Yuzuru Tamaru, Tsuyoshi Hatakeyama, Hirotaka Kouno, Yoshiyuki Shibata, Sho Tazuma, Takeshi Sudo, Midori Ishida, Yuki Hotehama, Hidemi Kane, Hisashi Tagashira, Sayo Yoshiyama, Mitsunobu Kubota, Shigeto Yoshida

PDF Pages: 1268-1279 Full Text (91) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Evolving survival patterns in pancreatic adenocarcinoma: a 23-year retrospective observational analysis

Tiago Cordeiro Felismino, Diego Rodrigues, Angelo Brito, Virgilio Silva, Lais Durant, Heber Ribeiro, Alessandro Diniz, Igor Farias, André Godoy, Silvio Torres, Maria Paula Curado, Felipe Coimbra

PDF Pages: 1280-1286 Full Text (141) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Comprehensive analysis identifies AMIGO2 as a potential prognosis biomarker of pancreatic adenocarcinoma

Jiawei Cao, Tong Zhou, Jiayu Chen, Dejin Shi, Xueting Liu, Changrui Qian, Guang Wu, Shaofei Yuan, Lan Li

PDF Pages: 1287-1304 Full Text (61) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Influence of pre-operative sarcopenia on post-operative hepatic steatosis after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma

Louis Caputo, Yasmina Richa, Kaja Balcer, César Beugniez, Mathilde Vermersch, Julien Bourry, Emeline Cailliau, Stephanie Truant, Mehdi El Amrani

PDF Pages: 1305-1313 Full Text (54) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Case Report: iMDT Corner

Camrelizumab plus sorafenib or apatinib achieved long-term survival in a patient with hepatocellular carcinoma and an Eastern Cooperative Oncology Group performance status of 3: a case report

Xin Wang, Guangbin Ji, Xi Chen, Hongbo Hu, Lianyue Zou, Haruhiko Takeda, Caiyun Zhou

PDF Pages: 1314-1320 Full Text (90) Reporting Checklist Peer Review File COI Form Open Access

Case Report

Liver transplantation in a patient with metastatic hepatocellular carcinoma after downstaging with single-agent immunotherapy: the first case report

Angelo Pirozzi, Celine Hoyek, Oluseyi Abidoye, Naohiro Okano, Michelle C. Nguyen, Thomas Byrne, Bashar Aqel, David Chascsa, Sadeer Alzubaidi, Lorenza Rimassa, Tanios Bekaii-Saab, Mitesh J. Borad

PDF Pages: 1321-1330 Full Text (230) Reporting Checklist Peer Review File COI Form Open Access